Automation of T-cell Expansion Using the iLine F.

logo Bristol Myers Squibb

A joint talk with Bristol Myers Squibb presented at the ASGCT digital event held on May 14, 2020.

The iLine F microscope integrates the fully automated workflow, sampling and recipe progression – see operations workflow below:

The graph on the left displays the average of 75 automated expansion runs (feeding & expansion), pink line; compared to manual feeding with automated expansion, blue line.

In conclusion, binding real-time Cell Quality Attribute (CQAs) monitoring (iLine F microscope) & media feeding results in:

  • an increased growth rate.
  • a higher cell density.

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